DNA methylation sequencing helps researchers investigate epigenetic regulation across the genome, from CpG-rich regulatory regions to genome-wide methylation patterns.

Novogene Europe offers a flexible portfolio of methylation sequencing workflows, including WGBS, RRBS, Enzyme Methyl-seq, TAPS+ and 5-base sequencing. Our scientific team can help select an appropriate approach based on sample type, DNA quality, study objectives and downstream analysis needs.

Flexible workflows for different research needs

Available options support both broad genome-wide profiling and more focused CpG-rich region analysis. Selected workflows can also accommodate challenging inputs such as FFPE DNA, cfDNA, fragmented DNA and low-input samples.

From methylation data to wider insight

Analysis can include genome-wide methylation profiling, differential methylation analysis and functional interpretation. Methylation data may also be integrated with gene expression and other omics datasets to investigate regulatory relationships and support pathway or candidate-gene prioritisation.

Explore the service flyer for an overview of available sequencing approaches, sample compatibility and project support.